28th May 2024

Intermittent fasting and mental health: Understanding the connection

In recent years, intermittent fasting has gained significant attention for its potential benefits in weight management and metabolic health. However, its impact on mental wellbeing is a topic that has sparked growing interest among researchers and health enthusiasts alike.

Today, we’re going to explore these intriguing benefits and the relationship between intermittent fasting and mental health. Let’s look at how this dietary approach may contribute to improved mental clarity, emotional wellbeing, and better overall psychological health.

The gut-brain axis and mental health

The gut-brain axis represents a complex interplay between the gut and the brain, intertwining various physiological and biochemical pathways. This intricate connection not only influences digestion but also plays a fundamental role in regulating your mood, cognition, and overall mental health.

Recent scientific research has illuminated the profound impact of gut microbiota on mental wellbeing. The gut microbiota, consisting of trillions of microorganisms inhabiting the gastrointestinal tract, actively communicate with the central nervous system through neural, hormonal, and immune pathways. This bidirectional communication enables the gut microbiota to influence brain function and behaviour, shaping emotional responses, stress resilience, and cognitive processes.

When the delicate balance of gut microbiota is disrupted, a state known as dysbiosis may ensue. This state may lead to adverse effects on mental health, and can lead to depression, anxiety, and even neurodegenerative diseases such as Alzheimer’s. Imbalances in gut microbiota composition can trigger systemic inflammation, impair neurotransmitter synthesis, and compromise the integrity of the gut barrier – all of which contribute to the development and exacerbation of mental health conditions.1

Intermittent fasting for mental Health and metabolic changes

Intermittent fasting also has the capacity to cause metabolic changes in your body, such as increased ketone production and improved insulin sensitivity. Ketones produced during fasting periods serve as an alternative fuel source for the brain, offering neuroprotective effects and promoting cognitive function. Additionally, enhanced insulin sensitivity facilitates glucose uptake by brain cells, optimising energy metabolism and neurotransmitter synthesis, which are essential for maintaining mood stability and cognitive performance.

In essence, the gut-brain axis serves as a pivotal nexus through which intermittent fasting influences mental health. By nurturing a symbiotic relationship between the gut and the brain, intermittent fasting can alleviate symptoms of mental health disorders, enhance emotional well-being, and promote cognitive resilience. As our understanding of the gut-brain axis continues to evolve, leveraging the therapeutic potential of intermittent fasting may offer novel avenues for supporting mental health and optimising overall wellness.2

What are the other connections between intermittent fasting and mental health?

Intermittent fasting for mental clarity

One key reason people choose this dietary option is the link between intermittent fasting for mental clarity and cognitive function. By promoting neuroplasticity and increasing the production of brain-derived neurotrophic factor (BDNF) – a protein that supports the growth and maintenance of nerve cells – intermittent fasting may help improve focus, concentration, and memory. Intermittent fasting also supports stable blood sugar levels to help prevent energy crashes and promote sustained mental alertness throughout the day.3

Intermittent fasting for emotional wellbeing

As well as intermittent fasting for mental clarity and maintaining good mental health, fasting also helps to regulate your emotional wellbeing. By stabilising blood sugar levels and promoting hormonal balance, intermittent fasting can help regulate mood and reduce the risk of mood swings and emotional fluctuations. Intermittent fasting may also stimulate the release of endorphins, neurotransmitters that promote feelings of happiness and wellbeing, leading to a more positive outlook and improved emotional resilience.4

Practical tips for incorporating intermittent fasting

If you’re interested in harnessing the mental health benefits of intermittent fasting, here are some practical tips to help you get started:

  • Start gradually: Begin with shorter fasting periods, such as the 12/12 method, and gradually increase the duration as your body adjusts.
  • Stay hydrated: Drink plenty of water and herbal tea during fasting periods to stay hydrated and support cognitive function.
  • Prioritise nutrient-dense foods: Focus on whole, nutrient-rich foods during eating windows to ensure you’re meeting your nutritional needs and supporting overall health.
  • Listen to your body: Pay attention to hunger cues, energy levels, and mood fluctuations during fasting periods. Adjust your fasting schedule as needed to suit your individual needs and preferences.
  • Seek professional guidance: If you have any underlying health conditions or concerns about intermittent fasting, consult a healthcare professional before making significant changes to your diet or lifestyle. It’s always a great idea to follow a programme such as The Fast 800 to help give you professional, expert guidance throughout.

Intermittent fasting and mental health – The Roundup

As we’ve explored today, there is a substantial connection between intermittent fasting and mental health, as it promotes gut health, enhances mental clarity, and supports emotional wellbeing. By incorporating intermittent fasting into your lifestyle, you can harness a tool that can optimise your mental health and unlock your full potential for happiness and vitality. Remember to approach intermittent fasting mindfully and seek guidance from healthcare professionals as needed to ensure a safe and sustainable approach to mental wellness.

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Looking to begin your path to a healthier, happier lifestyle? Whether you’re searching for a weight loss programme that gets results or for support with your intermittent fasting plan, The Fast 800 is ready to partner with you on your journey. Working with Dr Michael Mosley, we use the latest scientific research to create a game-changing approach to weight loss and healthy living. Our work is based on scientific evidence, encompassing diet, movement and mindfulness to create accessible solutions for a healthier life.

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Intermittent fasting for mental health – Frequently Asked Questions

What role does nutrition play in supporting mental health during intermittent fasting?

Proper nutrition is crucial for maintaining mental health during intermittent fasting. Adequate intake of essential nutrients, including vitamins, minerals, and omega-3 fatty acids, supports brain function and mood regulation. Focusing on nutrient-dense foods during eating windows ensures that your body receives the necessary nutrients for optimal mental wellbeing.

Does intermittent fasting have different effects on mental health for men and women?

While intermittent fasting can positively impact mental health for men and women, individual responses may vary. Women may experience fluctuations in mood, energy levels, and hunger cues due to hormonal changes throughout the menstrual cycle. It’s crucial for you to listen to your body and adjust your fasting approach accordingly to support your mental wellbeing.

Should I just rely on fasting to regulate my mental health?

Despite the connection between intermittent fasting and mental health, relying solely on fasting to regulate mental health may not be sufficient. While intermittent fasting can offer benefits for mental clarity, focus, and mood, it’s essential to adopt a holistic approach to mental health. This includes incorporating other lifestyle factors such as regular physical activity, adequate sleep, stress management techniques, and social support. Additionally, seeking professional guidance from a healthcare provider or mental health professional is important for addressing underlying mental health concerns.


Jeremy Appleton. The Gut-Brain Axis: Influence of Microbiota on Mood and Mental Health. Integr Med (Encinitas). 2018 Aug; 17(4): 28–32. PMID: 31043907.

Jeremy Appleton. The Gut-Brain Axis: Influence of Microbiota on Mood and Mental Health. Integr Med (Encinitas). 2018 Aug; 17(4): 28–32. PMID: 31043907.

Jip Gudden,1 Alejandro Arias Vasquez,1,2 and Mirjam Bloemendaal1. The Effects of Intermittent Fasting on Brain and Cognitive Function. Nutrients. 2021 Sep; 13(9): 3166. doi: 10.3390/nu13093166. PMID: 34579042.

Yiren Wang and Ruilin Wu. The Effect of Fasting on Human Metabolism and Psychological Health. Dis Markers. 2022; 2022: 5653739. doi: 10.1155/2022/5653739. PMID: 35035610.

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